Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855351 | 0.83 | RAB9A (0.45) | RAB9ASMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL20855345 | 0.83 | USP2 (0.41) | HTTL3MBTL1POLBHPGDKDM4E | |
| SCHEMBL8995883 | 0.82 | HTT (0.36) | HSD17B10HTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4396806 | 0.79 | NPC1 (0.41) | HTTRAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL20870952 | 0.75 | DAO (0.44) | RAB9ASMN1; SMN2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL22911695 | 0.74 | MAOB (0.34) | L3MBTL1LMNA | |
| SCHEMBL22911700 | 0.72 | — | — | |
| SCHEMBL20870953 | 0.71 | DAO (0.33) | L3MBTL1LMNA | |
| SCHEMBL4386341 | 0.70 | SLC6A2 (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL14168752 | 0.70 | ITGB1 (0.40) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929637-B | Sulfur-containing dihydro isoxazole compound and synthetic method thereof | 山东大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-113929637-A | Sulfur-containing dihydro isoxazole compound and synthetic method thereof | 山东大学 | 2022-01-14 | — | — | CN | disclosed |
| EP-2186410-B1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7833939-B2 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| WO-2010116121-A1 | PROCESSES FOR MAKING ISOXAZOLINE DERIVATIVES | SYNGENTA LIMITED (GB) | 2010-10-14 | — | — | WO | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| EP-1799657-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2009-12-02 | — | — | EP | disclosed |
| US-7465805-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1203768-B1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| CN-1673221-A | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-6841519-B1 | Isoxazoline derivatives and herbicides containing the same as the active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-01-11 | — | — | US | disclosed |
| CN-1170825-C | isoxazoline derivative and herbicide containing the same as active ingredient | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| CN-1491217-A | Isoxazoline derivatives and herbicides containing them as active ingredient | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |
| CN-1368965-A | isoxazoline derivative and herbicide containing the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2002-09-11 | — | — | CN | disclosed |
| EP-1203768-A1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256004-A1 | Herbicide compositions | DDT, CYP4X1, GLRX3 | HSD17B10 608/4885HTT 938/4885RAB9A 2464/4885 |
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | CYP4X1, CYP3A7, CYP4Z1 | HSD17B10 623/4885HTT 1683/4885RAB9A 3117/4885 |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | CYP4X1, PRDX5, CYP3A7 | HSD17B10 847/4885HTT 2681/4885RAB9A 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.