SCHEMBL8995905

SCHEMBL8995905

C[C@H](CN1CCN(c2cccccc2=O)CC1)NC(=O)c1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.49
ADRA1A P35348 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995898 0.80 DRD2 (0.44) ADRA1A
SCHEMBL8995901 0.80 DRD2 (0.44) ADRA1A
SCHEMBL11105049 0.74 DRD2 (0.59)
Acetic Acid SCHEMBL11091442 0.71 ABCB1 (0.50)
SCHEMBL30044824 0.71 KDM4E (0.56)
SCHEMBL11095362 0.71 ADRA2A (0.54) HTR1A
SCHEMBL11107336 0.70 ADRA2A (0.66)
SCHEMBL20341502 0.69 KDM4E (0.51)
SCHEMBL20341491 0.69 KDM4E (0.51)
SCHEMBL9145271 0.69 HDAC1 (0.56) HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5541179-A Tropon-2-one piperazine carboxamides as serotonergic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1996-07-30 US disclosed