Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.44 |
| ▸ | DRD3 | P35462 | 5/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995898 | 1.00 | DRD2 (0.44) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL7465581 | 0.83 | DRD2 (0.62) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL8014073 | 0.83 | DRD2 (0.62) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL7465587 | 0.83 | DRD2 (0.62) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL8995905 | 0.80 | HTR1A (0.49) | ADRA1A | |
| SCHEMBL5423523 | 0.78 | DRD2 (0.52) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL5423525 | 0.78 | DRD2 (0.52) | DRD2ADRA1ADRD3LPAR2 | |
| SCHEMBL11105049 | 0.74 | DRD2 (0.59) | DRD2DRD3 | |
| SCHEMBL11095362 | 0.71 | ADRA2A (0.54) | DRD2 | |
| Acetic Acid SCHEMBL11091442 | 0.70 | ABCB1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541179-A | Tropon-2-one piperazine carboxamides as serotonergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | claimed |
| US-5541179-A | Tropon-2-one piperazine carboxamides as serotonergic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |