SCHEMBL899596

SCHEMBL899596

C=Cc1ccc([SiH2]C(Cl)Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703792 0.80
SCHEMBL23493393 0.77 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HDAC8CHRNB2
Chloroform SCHEMBL28057528 0.77 ALDH1A1 (0.73) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL23493451 0.75 TP53 (0.44) ALDH1A1TSHRTDP1
SCHEMBL607229 0.72 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL1448791 0.72 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL28219512 0.72 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL473081 0.71 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL7639 0.71 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL23493407 0.70 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142500-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2006-06-29 US claimed
US-20050182191-A1 Multi-branched styrene-conjugated diene block copolymer and its preparation method KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2005-08-18 US claimed
US-6756448-B2 SYNDIOTACTIC; LIVING BUTADIENE OR ISOPRENE POLYMER BY ANIONIC POLYMERIZATION WITH ALKYLLITHIUM CATALYST AND THEN REACTION WITH A P-SILYLSTYRENE TERMINAL MODIFIER; FURTHER COPOLYMERIZATION WITH STYRENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-06-29 US claimed
US-20040059075-A1 Styrene copolymer KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2004-03-25 US claimed
JP-6184237-A None JP disclosed
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-26 US disclosed
EP-4570827-A1 CONJUGATED DIENE-BASED POLYMER, MOLDED BODY, PRODUCTION METHOD FOR CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND TIRE Asahi Kasei Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
EP-4134382-B1 HYDROGENATED CONJUGATED DIENE-BASED POLYMER, HYDROGENATED CONJUGATED DIENE-BASED POLYMER COMPOSITION, RUBBER COMPOSITION, AND METHOD FOR PRODUCING HYDROGENATED CONJUGATED DIENE-BASED POLYMER ASAHI CHEMICAL IND (JP) 2025-05-07 EP disclosed
CN-119497723-A Conjugated diene polymer, molded article, method for producing conjugated diene polymer, rubber composition, and tire 旭化成株式会社 2025-02-21 CN disclosed
CN-119462990-A Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition 旭化成株式会社 2025-02-18 CN disclosed
WO-2025028621-A1 MODIFIED CONJUGATED DIENE POLYMER, BALE, METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION, AND TIRE 旭化成株式会社 2025-02-06 WO disclosed
US-12215179-B2 Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, oil extended conjugated diene-based polymer, rubber composition, and tire ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-02-04 US disclosed
WO-1991012284-A1 FUNCTIONALIZED MULTISEQUENCED MACROMONOMERS AND PRODUCTION METHOD ELF ATOCHEM S.A. (FR) 1991-08-22 WO disclosed
EP-0442804-A1 Multi-block functionalized macromonomers and their method of manufacture ELF ATOCHEM S.A. (FR) 1991-08-21 EP disclosed
EP-0419314-A1 Process for preparing functionalised (meth)acrylic macromonomers and macromonomers so prepared ELF ATOCHEM S.A. (FR) 1991-03-27 EP disclosed
WO-1991003502-A1 METHOD FOR PRODUCING FUNCTIONALIZED (METH)ACRYLIC MACROMONOMERS AND MACROMONOMERS THUS OBTAINED ATOCHEM (FR) 1991-03-21 WO disclosed
US-4996266-A Branched elastomeric and block copolymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4906691-A Adhesive compositions made with condensed phase polymers and sheet materials coated therewith MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-06 US disclosed
US-4857618-A ELASTOMERIC, ANIONIC COPOLYMERS; ORGANOMETALLIC CONDENSING AGENT; PRESSURE SENSITIVE ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed
US-4857615-A Method of making condensed phase polymers MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055216-A1 Conjugated Diene-Based Polymer, Formed Body, Production Method for Conjugated Diene-Based Polymer, Rubber Composition, and Tire HMGB2, HMGB1, HMGB3 ALDH1A1 2948/4885TSHR 159/4885TDP1 1360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.