Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8995949 | 0.98 | HSD11B1 (0.41) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL8995970 | 0.82 | HTT (0.50) | SMN1; SMN2HTTKDM4EKMT2ANPC1 | |
| Iodide SCHEMBL8995956 | 0.81 | HTT (0.49) | HTTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL4624134 | 0.80 | SLC6A2 (0.42) | SMN1; SMN2HTTKMT2ANPC1RAB9A | |
| SCHEMBL10845894 | 0.77 | NFE2L2 (0.45) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL3645967 | 0.75 | NFE2L2 (0.44) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL5716706 | 0.73 | TAS1R3 (0.46) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL3365928 | 0.72 | NFE2L2 (0.44) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL11792870 | 0.71 | SMN1; SMN2 (0.44) | HSD11B1SMN1; SMN2HTTTAS1R3TAS1R1 | |
| SCHEMBL10339057 | 0.71 | HPGD (0.44) | SMN1; SMN2KDM4ELMNAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572986-B1 | Assay for serum cholinesterase | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-28 | — | — | EP | claimed |
| EP-0572986-B1 | Assay for serum cholinesterase | JOHNSON & JOHNSON CLIN DIAG (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0572986-A1 | Assay for serum cholinesterase | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1993-12-08 | — | — | EP | disclosed |