Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996347 | 0.89 | TTR (0.43) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL8996320 | 0.84 | EGFR (0.45) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL8996340 | 0.78 | KDM4E (0.54) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL9008523 | 0.77 | TTR (0.43) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8996365 | 0.77 | KDM4E (0.53) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL5613348 | 0.77 | ALDH1A1 (0.73) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL8996327 | 0.76 | ALDH1A1 (0.51) | TTRKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8996422 | 0.75 | KMT2A (0.50) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL14003223 | 0.75 | TTR (0.71) | TTRADORA3ADORA2AKDM4EALDH1A1 | |
| SCHEMBL29227280 | 0.74 | PDE5A (0.50) | KDM4EALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | claimed |
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |