Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008524 | 0.85 | MAPT (0.46) | ADORA2AKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL11625180 | 0.79 | MAOB (0.35) | MEN1ALDH1A1LMNATP53MAPT | |
| SCHEMBL8996439 | 0.77 | TTR (0.57) | TTRPIM1ADORA3ADORA2AKDM4E | |
| SCHEMBL11619908 | 0.76 | PTPRC (0.35) | MEN1LMNAMAPTHTTKMT2A | |
| SCHEMBL9008510 | 0.72 | TTR (0.53) | TTRGAPDHPIM1BACE1ADORA3 | |
| SCHEMBL29227279 | 0.72 | HSD17B10 (0.47) | TTRGAPDHBACE1KDM4EMEN1 | |
| SCHEMBL30554756 | 0.70 | ACHE (0.48) | GAPDHBACE1ADORA2AMEN1ALDH1A1 | |
| SCHEMBL29227277 | 0.70 | ACHE (0.48) | GAPDHBACE1ADORA2AMEN1ALDH1A1 | |
| SCHEMBL29227280 | 0.70 | PDE5A (0.50) | KDM4EMEN1ALDH1A1LMNAHSP90AA1 | |
| SCHEMBL29551111 | 0.70 | MAPT (0.60) | TTRPIM1ADORA3ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | claimed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | claimed |
| US-5484935-A | Pharmaceutical compounds | LILLY INDUSTRIES LIMITED (GB) | 1996-01-16 | — | — | US | disclosed |
| EP-0638562-A1 | Anthraquinone derivatives useful in the treatment of cancer and osteoartritis | LILLY INDUSTRIES LIMITED (GB) | 1995-02-15 | — | — | EP | disclosed |