Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996320 | 0.77 | EGFR (0.45) | ALDH1A1MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL8996439 | 0.76 | TTR (0.57) | ALDH1A1MAPTTDP1MAPK1LMNA | |
| SCHEMBL8996325 | 0.74 | F7 (0.51) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL22909075 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL15413504 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL8996347 | 0.73 | TTR (0.43) | ALDH1A1MAPTMAPK1LMNAHPGD | |
| Danthron SCHEMBL29356886 | 0.72 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| Danthron SCHEMBL30544826 | 0.72 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| Danthron SCHEMBL83688 | 0.72 | MAPT (1.00) | ALDH1A1MAPTTSHRTDP1MAOA | |
| SCHEMBL28012200 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MAPTTSHRTDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| CN-1079732-A | Medical compounds | LILLY INDUSTRIES LTD (GB) | 1993-12-22 | — | — | CN | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |