SCHEMBL8996583

SCHEMBL8996583

CC(CC1CCCCC1)CC1(C)OCC(CN2CCCCC2)O1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.38
ADRA2C P18825 1/20 0.38
GAA P10253 1/20 0.36
HTR1A P08908 3/20 0.34
TMEM97 Q5BJF2 3/20 0.33
SIGMAR1 Q99720 3/20 0.33
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996657 0.83 GAA (0.42) CHRM5ADRA2CGAAHTR1ATMEM97
SCHEMBL9003941 0.70 GAA (0.39) CHRM5ADRA2CGAAHTR1ATMEM97
SCHEMBL8996683 0.69 ADRA2C (0.40) CHRM5ADRA2CGAAHTR1ATMEM97
SCHEMBL8996578 0.69 ADRA2C (0.40) CHRM5ADRA2CGAAHTR1ATMEM97
SCHEMBL10761463 0.68 GAA (0.39) ADRA2CGAAHTR1ATMEM97SIGMAR1
SCHEMBL10761458 0.68 GAA (0.39) ADRA2CGAAHTR1ATMEM97SIGMAR1
SCHEMBL9426366 0.64 GAA (0.53) GAAHTR1ATMEM97SIGMAR1ADRA1A
SCHEMBL9003942 0.63 GAA (0.37) CHRM5ADRA2CGAAHTR1ATMEM97
SCHEMBL9853850 0.63 GAA (0.79) GAAHTR1ATMEM97SIGMAR1LMNA
SCHEMBL3155857 0.61 CYP1A2 (0.40) CHRM5ADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5571930-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-11-05 US disclosed
US-5493034-A Intermediate for pesticidal aminomethylheterocyclic compounds BAYER AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5447927-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1995-09-05 US disclosed
US-5376660-A An aminomethyl-1,4-dioxaspiro(4,5)decanes pesticides or fungicides BAYER AKTIENGESELLSCHAFT (DE) 1994-12-27 US disclosed
EP-0355597-B1 SUBSTITUTED DIOXOLANYLETHYLAMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES BAYER AG (DE) 1993-06-09 EP disclosed
US-5177103-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-01-05 US disclosed
EP-0359979-B1 AMINOMETHYLHETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN PESTICIDES, AND INTERMEDIATES BAYER AG (DE) 1992-12-30 EP disclosed
US-5010101-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
US-4985421-A Fungicidal substituted dioxolanylethylamine BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed
EP-0359979-A1 Aminomethylheterocyclic compounds, process for their preparation, their use in pesticides, and intermediates BAYER AG (DE) 1990-03-28 EP disclosed
EP-0355597-A1 Substituted dioxolanylethylamines, process for their preparation, their use in pesticides, and intermediates BAYER AG (DE) 1990-02-28 EP disclosed