Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733371 | 0.78 | FBP1 (0.51) | LMNAALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL10730171 | 0.77 | PARG (0.43) | KAT6ACYP2A6LMNAMEN1KMT2A | |
| SCHEMBL2752345 | 0.76 | CYP2A6 (0.54) | KAT6ACYP2A6ITGAVLMNAALDH1A1 | |
| SCHEMBL8240985 | 0.75 | CASP1 (0.56) | BCL2L1MCL1LMNAMEN1KMT2A | |
| SCHEMBL10732567 | 0.75 | CYP2A6 (0.52) | CYP2A6ALDH1A1 | |
| SCHEMBL10736013 | 0.74 | GAA (0.53) | GAALMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3954909 | 0.73 | POLB (0.58) | ITGAVSLC1A3SLC1A2GAAFLT1 | |
| SCHEMBL10784100 | 0.73 | POLB (0.58) | ITGAVSLC1A3SLC1A2GAAFLT1 | |
| SCHEMBL8997298 | 0.73 | NAT1 (0.50) | KAT6ABCL2L1MCL1FLT1FLT4 | |
| SCHEMBL4630193 | 0.72 | CYP2A6 (0.48) | KAT6ACYP2A6BCL2L1ITGAVLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512681-A | HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-30 | — | — | US | claimed |