Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997381 | 1.00 | ALOX5 (0.50) | ALOX5HDAC2LTB4RLTB4R2TRPM8 | |
| SCHEMBL9877155 | 0.79 | HDAC2 (0.57) | ALOX5HDAC2TRPM8NPC1L3MBTL1 | |
| SCHEMBL9590158 | 0.77 | HDAC2 (0.59) | HDAC2LTB4RTRPM8TDP1NPC1 | |
| SCHEMBL2622484 | 0.73 | HDAC2 (0.59) | HDAC2LTB4RTDP1KDM4EMAPK1 | |
| SCHEMBL9707327 | 0.73 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9376883 | 0.73 | ALOX5 (0.51) | ALOX5TDP1KDM4EMAPK1 | |
| SCHEMBL11280951 | 0.73 | NPC1 (0.81) | HDAC2LTB4RLTB4R2TRPM8NPC1 | |
| SCHEMBL11280949 | 0.73 | NPC1 (0.81) | HDAC2LTB4RLTB4R2TRPM8NPC1 | |
| SCHEMBL9376877 | 0.73 | ALOX5 (0.51) | ALOX5TDP1KDM4EMAPK1 | |
| SCHEMBL9475050 | 0.72 | ALOX5 (0.80) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8092191-A | — | — | None | — | — | JP | disclosed |
| JP-H0892191-A | HYDROXAMIC ACID DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THE DERIVATIVE | TERUMO CORP | 1996-04-09 | — | — | JP | disclosed |