Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | MMP9 | P14780 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALAD | P13716 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503470 | 0.94 | LMNA (0.62) | LMNAMAPK1LDHACYP1A2FPR2 | |
| SCHEMBL10170603 | 0.94 | LMNA (0.62) | LMNAMAPK1LDHACYP1A2FPR2 | |
| SCHEMBL323295 | 0.94 | LMNA (0.62) | LMNAMAPK1LDHACYP1A2FPR2 | |
| SCHEMBL29903941 | 0.94 | LMNA (0.62) | LMNAMAPK1LDHACYP1A2FPR2 | |
| SCHEMBL7564021 | 0.83 | LMNA (0.74) | LMNAMAPK1PTGS2CYP1A2 | |
| SCHEMBL8993579 | 0.83 | LMNA (0.74) | LMNAMAPK1PTGS2CYP1A2 | |
| SCHEMBL7564005 | 0.83 | LMNA (0.74) | LMNAMAPK1PTGS2CYP1A2 | |
| SCHEMBL275597 | 0.82 | LMNA (0.79) | LMNAMAPK1PTGS2BLMNPSR1 | |
| SCHEMBL8997286 | 0.81 | LMNA (0.58) | LMNAMAPK1MMP3PTGS2BLM | |
| SCHEMBL14525901 | 0.80 | CES2 (0.53) | LMNAALDH1A1CYP1A2HAO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459455-B1 | Process for producing optically active alpha-hydroxyesters | CHISSO CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5248610-A | Transesterification | CHISSO CORPORATION (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0459455-A2 | Process for producing optically active alpha-hydroxyesters | CHISSO CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |