Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997450 | 0.83 | GSK3B (0.61) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL11365527 | 0.82 | MAPT (0.56) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL3181886 | 0.80 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL3373429 | 0.80 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL5317014 | 0.78 | GSK3B (0.64) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL13191468 | 0.78 | MAPT (0.45) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL9820966 | 0.78 | LMNA (0.45) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL2151966 | 0.78 | GSK3B (0.64) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL221282 | 0.78 | MAPT (0.57) | LMNACYP1A2CYP3A4MAOAMEN1 | |
| SCHEMBL13811954 | 0.78 | HDAC3 (0.55) | LMNACYP1A2CYP3A4MAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221771-A | Activated polymers and conjugates thereof | XOMA CORPORATION (US) | 1993-06-22 | — | — | US | disclosed |
| US-5157099-A | Activated polymers and conjugates thereof | XOMA CORPORATION (US) | 1992-10-20 | — | — | US | disclosed |
| US-5103039-A | Activated polymers and conjugates thereof | XOMA CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |
| US-5090914-A | Activated polymers and conjugates thereof | XOMA CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |
| US-5081295-A | Activated polyers and conjugates thereof | XOMA CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| US-4052212-A | ETHER-ESTER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-10-04 | — | — | US | disclosed |