Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11804931 | 0.71 | BLM (0.38) | TSHRSMN1; SMN2MAPTFAAHKMT2A | |
| SCHEMBL28459568 | 0.68 | ALOX5 (0.46) | SMN1; SMN2MAPTKMT2A | |
| Bromide SCHEMBL8997510 | 0.67 | — | — | |
| SCHEMBL9278544 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL8997569 | 0.66 | TSHR (0.34) | TSHRSMN1; SMN2MAPTFAAHKMT2A | |
| SCHEMBL126980 | 0.66 | — | — | |
| Bromide SCHEMBL8997565 | 0.65 | PKM (0.34) | TSHR | |
| SCHEMBL2059972 | 0.65 | TSHR (0.33) | TSHRSMN1; SMN2MAPTFAAHKMT2A | |
| Hydrochloric Acid SCHEMBL10750519 | 0.65 | — | — | |
| Iodide SCHEMBL11848669 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5560814-A | USE OF LOW CONCENTRATIONS FOR THE ELECTRODEPOSITION OF NICKEL ON STEEL OR BRASS SHAPES | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-01 | — | — | US | disclosed |