Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325237 | 0.80 | FAAH (0.31) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL21404674 | 0.79 | ACHE (0.49) | ACHE | |
| SCHEMBL6249670 | 0.78 | CHRNB2 (0.44) | SMN1; SMN2CYP2D6CHRNB2CHRNA4 | |
| SCHEMBL6249674 | 0.78 | CHRNB2 (0.44) | SMN1; SMN2CYP2D6CHRNB2CHRNA4 | |
| SCHEMBL23111386 | 0.77 | TSHR (0.46) | TSHRSMN1; SMN2MAPTPKMFAAH | |
| SCHEMBL22400737 | 0.77 | ACHE (0.62) | ACHE | |
| SCHEMBL5185791 | 0.75 | HRH4 (0.35) | TSHRMAPTFAAHACHEKMT2A | |
| SCHEMBL6266348 | 0.75 | TSHR (0.48) | TSHRSMN1; SMN2HPGDALDH1A1CYP3A4 | |
| SCHEMBL3793027 | 0.75 | TSHR (0.48) | TSHRSMN1; SMN2HPGDALDH1A1CYP3A4 | |
| SCHEMBL4458944 | 0.74 | ACHE (0.47) | TSHRSMN1; SMN2MAPTFAAHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512400-B1 | Multicomponent system for producing a dental material | MUEHLBAUER ERNST GMBH & CO KG (DE) | 2013-09-25 | — | — | EP | disclosed |
| EP-2237763-B1 | MATERIAL FOR BUILDING UP STUMPS | MUEHLBAUER ERNST GMBH & CO KG (DE) | 2013-05-15 | — | — | EP | disclosed |
| EP-2198824-B1 | Polymerizable dental material with initiator system | MUEHLBAUER ERNST GMBH & CO KG (DE) | 2013-02-13 | — | — | EP | disclosed |
| US-8329776-B2 | Dental composition containing a polyfunctional (meth)acrylate comprising urethane, urea or amide groups, method of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120259032-A1 | MULTICOMPONENT SYSTEM FOR PRODUCING A DENTAL MATERIAL | MUHLBAUER TECHNOLOGY GMBH (DE) | 2012-10-11 | — | — | US | disclosed |
| US-20110053116-A1 | DENTAL COMPOSITION CONTAINING A POLYFUNCTIONAL (METH)ACRYLATE COMPRISING URETHANE, UREA OR AMIDE GROUPS, METHOD OF PRODUCTION AND USE THEREOF | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2011-03-03 | — | — | US | disclosed |
| EP-2198824-A1 | Polymerizable dental material with initiator system | Ernst Mühlbauer GmbH & Co.KG (DE) | 2010-06-23 | — | — | EP | disclosed |
| EP-2072028-A1 | Stump construction | Ernst Mühlbauer GmbH & Co.KG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1720506-B1 | FILLED POLYMERISABLE DENTAL MATERIAL AND METHOD FOR THE PRODUCTION THEREOF | MUEHLBAUER ERNST GMBH & CO KG (DE) | 2008-11-26 | — | — | EP | disclosed |
| EP-1913927-A1 | Polymerisable dental material with nano-diamond | Ernst Mühlbauer GmbH & Co.KG (DE) | 2008-04-23 | — | — | EP | disclosed |
| EP-1570831-A1 | Polymerisable dental material containing a filler | Ernst Mühlbauer GmbH & Co.KG (DE) | 2005-09-07 | — | — | EP | disclosed |
| EP-1267797-B1 | TWO-COMPONENT DENTAL MATERIALS HAVING A LOW SETTING TEMPERATURE | 3M ESPE AG (DE) | 2005-08-24 | — | — | EP | disclosed |
| US-6852775-B1 | Polymerizable dental compositions | 3M ESPE AG (DE) | 2005-02-08 | — | — | US | disclosed |
| EP-1194110-B1 | POLYMERIZABLE DENTAL SUBSTANCE | 3M ESPE AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| EP-1267797-A1 | TWO-COMPONENT DENTAL MATERIALS HAVING A LOW SETTING TEMPERATURE | 3M Espe AG (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-1194110-A1 | POLYMERIZABLE DENTAL SUBSTANCE | ESPE Dental AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001076536-A1 | TWO-COMPONENT DENTAL MATERIALS HAVING A LOW SETTING TEMPERATURE | 3M ESPE AG (DE) | 2001-10-18 | — | — | WO | disclosed |
| WO-2000078271-A1 | POLYMERIZABLE DENTAL SUBSTANCE | 3M ESPE AG (DE) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053116-A1 | DENTAL COMPOSITION CONTAINING A POLYFUNCTIONAL (METH)ACRYLATE COMPRISING URETHANE, UREA OR AMIDE GROUPS, METHOD OF PRODUCTION AND USE THEREOF | MUS81, MAT1A, SMCHD1 | TSHR 3008/4885SMN1; SMN2 2574/4885MAPT 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.