Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11804931 | 0.76 | BLM (0.38) | ALDH1A1TSHR | |
| SCHEMBL9278544 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL10750519 | 0.69 | — | — | |
| Iodide SCHEMBL11848669 | 0.69 | — | — | |
| SCHEMBL20734582 | 0.68 | ALDH1A1 (0.42) | HPGDALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL10991011 | 0.68 | LMNA (0.32) | TSHR | |
| Bromide SCHEMBL8997507 | 0.65 | TSHR (0.33) | TSHR | |
| Hydrochloric Acid SCHEMBL8997569 | 0.63 | TSHR (0.34) | TSHR | |
| SCHEMBL23135474 | 0.63 | SMN1; SMN2 (0.61) | PKMHPGDHTTTSHR | |
| SCHEMBL11065369 | 0.62 | GAA (0.49) | HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5560814-A | USE OF LOW CONCENTRATIONS FOR THE ELECTRODEPOSITION OF NICKEL ON STEEL OR BRASS SHAPES | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-01 | — | — | US | disclosed |