Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997619 | 0.90 | GHSR (0.35) | GHSRKCNH2ADRB2ADRB1TSHR | |
| SCHEMBL8997596 | 0.89 | GHSR (0.35) | GHSRKCNH2ADRB2ADRB1TSHR | |
| SCHEMBL8997626 | 0.88 | GHSR (0.35) | GHSRKCNH2ADRB2ADRB1TSHR | |
| SCHEMBL8612146 | 0.85 | GHSR (0.42) | GHSRKCNH2ADRB2ADRB1TSHR | |
| SCHEMBL8997886 | 0.83 | PRMT5 (0.31) | GHSRPRMT5WDR77 | |
| SCHEMBL8997623 | 0.81 | GHSR (0.34) | GHSRKCNH2 | |
| SCHEMBL8997612 | 0.81 | SYK (0.41) | TSHRCYP1A2CYP2C9 | |
| SCHEMBL8997715 | 0.78 | CPB2 (0.31) | GHSR | |
| SCHEMBL8559137 | 0.78 | GHSR (0.39) | GHSRHTR1AMTNR1AMTNR1B | |
| SCHEMBL8560312 | 0.78 | GHSR (0.39) | GHSRHTR1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |