Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921978 | 0.95 | KDM4E (0.70) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8444672 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8442541 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8444727 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8445875 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8445695 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8440798 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8441371 | 0.93 | KDM4E (0.68) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8552151 | 0.91 | ALDH1A1 (0.71) | KDM4EPOLBALDH1A1TSHRHTT | |
| SCHEMBL8722151 | 0.84 | KDM4E (0.70) | KDM4EPOLBALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486900-B1 | Process for the preparation of indoles | BAYER AG (DE) | 1996-09-04 | — | — | EP | disclosed |
| US-5179211-A | PROCESS FOR THE PREPARATION OF INDOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | disclosed |
| EP-0486900-A2 | Process for the preparation of indoles | BAYER AG (DE) | 1992-05-27 | — | — | EP | disclosed |
| US-4688059-A | 3-ARYL(OR HETEROARYL)-3-(OXY OR THIO)PHTHALIDE AS REAGENT IN CARBONLESS DUPLICATING SYSTEM | THE HILTON-DAVIS CHEMICAL CO. (US) | 1987-08-18 | — | — | US | disclosed |
| US-4535172-A | FOR CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-08-13 | — | — | US | disclosed |