Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HTR6 | P50406 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998008 | 0.91 | KDM4E (0.72) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL4921978 | 0.89 | KDM4E (0.70) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8440798 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8444672 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8444727 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8442541 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8445875 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8441371 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL8445695 | 0.87 | KDM4E (0.68) | ALDH1A1HTTTSHRKDM4EPOLB | |
| SCHEMBL28138965 | 0.85 | ALDH1A1 (0.71) | ALDH1A1HTTTSHRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219888-A1 | PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | MAGICMED INDUSTRIES INC. (CA) | 2023-07-13 | — | — | US | disclosed |
| WO-2020191208-A1 | PROSTAGLANDIN RECEPTOR EP2 ANTAGONISTS, DERIVATIVES, AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2020-09-24 | — | — | WO | disclosed |
| EP-2518052-B1 | Substituted 4-aminocyclohexane derivatives | GRUENENTHAL GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-8222381-B2 | Derivatives of monosaccharides for drug discovery | ALCHEMIA LIMITED (AU) | 2012-07-17 | — | — | US | disclosed |
| EP-1406872-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |
| CN-1014060-B | METHOD FOR PREPARAING ORTHO-AZONAPHTHALENE COMPOUND | IMP CHEMICAL IND PAN AMERICAL (US) | 1991-09-25 | — | — | CN | disclosed |
| EP-0205272-B1 | CINNOLINE DERIVATIVES | ICI AMERICAS INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| US-4886800-A | Substituted cinnoline derivatives as CNS depressants | ICI AMERICAS INC. (US) | 1989-12-12 | — | — | US | disclosed |
| CN-86104358-A | The preparation method of cinnoline compound | — | 1987-04-01 | — | — | CN | disclosed |
| EP-0205272-A2 | Cinnoline derivatives | ICI AMERICAS INC. (US) | 1986-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219888-A1 | PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | AANAT, ACAT2, PCYT1A | ALDH1A1 531/4885HTT 4285/4885TSHR 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.