Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998061 | 0.90 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8998058 | 0.87 | LMNA (0.34) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9407130 | 0.84 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9835963 | 0.81 | RORC (0.39) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9427372 | 0.80 | LMNA (0.34) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8998049 | 0.79 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8998044 | 0.79 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9835450 | 0.78 | NPSR1 (0.43) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9427678 | 0.78 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL9836348 | 0.77 | RORC (0.37) | L3MBTL1ALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |