Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247126 | 0.91 | CUL4A (0.41) | TDP1ALDH1A1CYP3A4HPGDCUL4A | |
| SCHEMBL9256733 | 0.89 | TDP1 (0.31) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL9814276 | 0.88 | CUL4A (0.44) | TDP1ALDH1A1CYP3A4HPGDCUL4A | |
| SCHEMBL7571714 | 0.84 | — | — | |
| SCHEMBL7220398 | 0.81 | NPC1 (0.33) | TDP1ALDH1A1CYP3A4HPGDNPC1 | |
| SCHEMBL7003782 | 0.81 | ALDH1A1 (0.47) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL8603030 | 0.79 | CUL4A (0.40) | ALDH1A1HPGDCUL4ANPC1MAPT | |
| SCHEMBL7931545 | 0.77 | TDP1 (0.45) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL8485314 | 0.77 | CUL4A (0.44) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL9836317 | 0.77 | PPOX (0.40) | TDP1ALDH1A1CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |