Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247126 | 0.84 | CUL4A (0.41) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL8998063 | 0.81 | TDP1 (0.32) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL7571714 | 0.80 | — | — | |
| SCHEMBL9256733 | 0.80 | TDP1 (0.31) | ALDH1A1HPGDCYP3A4TDP1 | |
| SCHEMBL7003782 | 0.78 | ALDH1A1 (0.47) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL7219984 | 0.78 | GAA (0.39) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL9814276 | 0.76 | CUL4A (0.44) | ALDH1A1HPGDCYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL9530045 | 0.76 | LMNA (0.57) | MAPTALDH1A1HPGDTDP1KDM4E | |
| SCHEMBL7682549 | 0.73 | GAA (0.41) | NPC1MAPTRAB9AALDH1A1HPGD | |
| SCHEMBL8603030 | 0.73 | CUL4A (0.40) | NPC1MAPTRAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528455-B1 | Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |
| EP-1237879-A1 | PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044204-A1 | PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-21 | — | — | WO | disclosed |