Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998063 | 0.89 | TDP1 (0.32) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL7247126 | 0.84 | CUL4A (0.41) | TDP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL7571714 | 0.82 | — | — | |
| SCHEMBL9814276 | 0.81 | CUL4A (0.44) | TDP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL7220398 | 0.80 | NPC1 (0.33) | TDP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL7003782 | 0.80 | ALDH1A1 (0.47) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL30987203 | 0.76 | KEAP1 (0.39) | TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL7931545 | 0.76 | TDP1 (0.45) | TDP1ALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL9836317 | 0.76 | PPOX (0.40) | TDP1ALDH1A1CYP3A4HPGD | |
| SCHEMBL7021771 | 0.76 | PPOX (0.40) | TDP1ALDH1A1CYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |