4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL8998523

COC1(OC)NC(=N)c2ccccc21.Cc1ccc(C(=O)O)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SRD5A2 P31213 2/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GAA P10253 2/20 0.38
PKM P14618 1/20 0.38
AKR1C3 P42330 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 2/20 0.36
CA12 O43570 2/20 0.36
CA9 Q16790 2/20 0.36
SCN2A Q99250 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3129229 0.81 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2KMT2AKDM4EHPGD
Succinic Acid SCHEMBL7823343 0.81 APEX1 (0.44) ALDH1A1GAACA12CA9TDP1
Dodecanoate SCHEMBL7826770 0.73 GPR84 (0.41) ALDH1A1CES2CES1MEN1KMT2A
SCHEMBL7829810 0.70 TP53 (0.33) ALDH1A1MEN1KMT2ATDP1L3MBTL1
4-Methylbenzoic Acid SCHEMBL14723409 0.69 ALDH1A1 (0.85) ALDH1A1SMN1; SMN2SRD5A2CES2CES1
4-Methylbenzoic Acid SCHEMBL7940172 0.69 ALDH1A1 (0.85) ALDH1A1SMN1; SMN2SRD5A2CES2CES1
4-Methylbenzoic Acid SCHEMBL27936299 0.69 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2SRD5A2CES2CES1
Benzoic Acid SCHEMBL3897333 0.67 ALDH1A1 (0.80) ALDH1A1SMN1; SMN2SRD5A2CES2CES1
Terephthalic Acid SCHEMBL28195120 0.67 ALDH1A1 (0.80) ALDH1A1SMN1; SMN2SRD5A2CES2CES1
Terephthalic Acid SCHEMBL7744567 0.67 ALDH1A1 (0.80) ALDH1A1SMN1; SMN2SRD5A2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8225753-A None JP disclosed
JP-H08225753-A CARBOXYLATE SALT, ITS PRODUCTION AND HEAT-SENSITIVE RECORDING MATERIAL USING THE SALT COMPOUND MITSUI TOATSU CHEM INC 1996-09-03 JP disclosed