Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CPN1 | P15169 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424114 | 0.93 | CYP3A4 (0.58) | MAOACYP3A4CASP1RECQLCPN1 | |
| SCHEMBL28356672 | 0.88 | ALDH1A1 (0.57) | MAOACYP3A4CASP1RECQLCPN1 | |
| SCHEMBL21380576 | 0.84 | MAOA (0.41) | MAOACYP3A4CASP1RECQLCPN1 | |
| SCHEMBL28091155 | 0.83 | ALDH1A1 (0.50) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL7763010 | 0.83 | ALDH1A1 (0.50) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL27925316 | 0.80 | CA12 (0.64) | CYP3A4CASP1RECQLCPN1CPB2 | |
| SCHEMBL5832415 | 0.79 | MAOA (0.48) | MAOACYP3A4CASP1RECQLCPN1 | |
| SCHEMBL17064637 | 0.79 | CA1 (0.57) | MAOACYP3A4CASP1RECQLCPN1 | |
| SCHEMBL22051091 | 0.79 | CYP3A4 (0.56) | CYP3A4CASP1TSHRMAOBTDP1 | |
| SCHEMBL22050359 | 0.78 | MEN1 (0.40) | CYP3A4CASP1RECQLCPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592197-A | Preparation method of besifloxacin hydrochloride | GUANGXI RENHENG PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | claimed |
| CN-106867251-B | A kind of prepreg and the method that honeycomb core is prepared by it | 杭州铠恒新材料有限公司 | 2019-03-12 | — | — | CN | disclosed |
| US-20180305830-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2018-10-25 | — | — | US | disclosed |
| EP-3362588-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | Covestro Deutschland AG (DE) | 2018-08-22 | — | — | EP | disclosed |
| CN-103012264-B | The method for splitting of 3 substituted-amino hexahydro 1H azepans | 常州亚邦制药有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-106867251-A | A kind of prepreg and the method that honeycomb core is prepared by it | 杭州昂瑞阻燃科技有限公司 | 2017-06-20 | — | — | CN | disclosed |
| WO-2017064133-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2017-04-20 | — | — | WO | disclosed |
| CN-104592197-A | Preparation method of besifloxacin hydrochloride | GUANGXI RENHENG PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | disclosed |
| EP-0543986-B1 | POLYMERIC RESIN FOR PEPTIDE SYNTHESIS | RES & DIAGNOSTIC ANTIBODIES (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0543986-A4 | POLYMERIC RESIN FOR PEPTIDE SYNTHESIS | — | 1993-11-10 | — | — | EP | disclosed |
| EP-0543986-A1 | POLYMERIC RESIN FOR PEPTIDE SYNTHESIS. | RES & DIAGNOSTIC ANTIBODIES (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5198531-A | POLYMERIC RESIN FOR PEPTIDE SYNTHESIS | RESEARCH DIAGNOSTIC ANTIBODIES (US) | 1993-03-30 | — | — | US | disclosed |
| WO-1992022591-A1 | POLYMERIC RESIN FOR PEPTIDE SYNTHESIS | RESEARCH & DIAGNOSTIC ANTIBODIES (US) | 1992-12-23 | — | — | WO | disclosed |
| EP-0053815-B1 | 2-OXOAZETIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305830-A1 | METHOD FOR PRODUCING AMINO-FUNCTIONAL AROMATIC COMPOUNDS | DDC, BTD, BCAT1 | MAOA 200/4885CYP3A4 98/4885CASP1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.