Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 1.00 |
| ▸ | EGFR | P00533 | 12/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999067 | 0.89 | SRC (1.00) | SRCEGFRFGFR1 | |
| SCHEMBL8999420 | 0.87 | SRC (1.00) | SRCEGFRFGFR1 | |
| SCHEMBL1527703 | 0.83 | SRC (1.00) | SRCEGFRFGFR1ALDH1A1 | |
| SCHEMBL8999138 | 0.78 | SRC (1.00) | SRCEGFRFGFR1ALDH1A1 | |
| SCHEMBL8998829 | 0.78 | SRC (1.00) | SRCEGFRFGFR1ALDH1A1 | |
| SCHEMBL8998945 | 0.76 | SRC (1.00) | SRCEGFRFGFR1RAB9A | |
| SCHEMBL8998915 | 0.76 | SRC (0.81) | SRCEGFRFGFR1ALDH1A1 | |
| SCHEMBL8999317 | 0.76 | SRC (0.75) | SRCEGFRFGFR1ALDH1A1 | |
| SCHEMBL9157458 | 0.76 | CREBBP (0.76) | SRCRAB9ACREBBPALDH1A1TSHR | |
| SCHEMBL677770 | 0.73 | RAB9A (1.00) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | disclosed |