Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998813 | 0.86 | MMP8 (0.47) | MMP8PIN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1125008 | 0.76 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11TSHRCYP2C9 | |
| SCHEMBL9086579 | 0.74 | LMNA (0.51) | MMP8CES2CES1PIN1LMNA | |
| SCHEMBL8998946 | 0.73 | MMP8 (0.43) | MMP8CES2CES1PIN1LMNA | |
| Bicarbonate SCHEMBL28193127 | 0.71 | MMP8 (0.53) | MMP8PIN1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8998992 | 0.71 | MMP8 (0.49) | MMP8PIN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL27419364 | 0.70 | MMP8 (0.46) | MMP8PIN1LMNASMN1; SMN2MEN1 | |
| SCHEMBL19210801 | 0.70 | MMP8 (0.52) | MMP8PIN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9126861 | 0.70 | MMP8 (0.54) | MMP8PIN1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1661290 | 0.70 | MMP8 (0.54) | MMP8PIN1SMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |