Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999047 | 0.86 | MMP8 (0.43) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL8998992 | 0.84 | MMP8 (0.49) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL5084136 | 0.79 | LMNA (0.55) | MMP8PIN1NPC1MEN1KMT2A | |
| Bicarbonate SCHEMBL28193127 | 0.76 | MMP8 (0.53) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL10910013 | 0.75 | MEN1 (0.46) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL27419364 | 0.75 | MMP8 (0.46) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL16430281 | 0.74 | MMP8 (0.54) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL1661290 | 0.74 | MMP8 (0.54) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL2301980 | 0.74 | MMP8 (0.54) | MMP8PIN1NPC1MEN1KMT2A | |
| SCHEMBL21715044 | 0.73 | HSD11B1 (0.46) | MMP8MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |