Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998830 | 0.86 | PIN1 (0.45) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL15489465 | 0.77 | PIN1 (0.45) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL2993639 | 0.76 | PIN1 (0.50) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL15419570 | 0.75 | PIN1 (0.49) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL8999047 | 0.73 | MMP8 (0.43) | MMP8PIN1CES2CES1LMNA | |
| SCHEMBL11069746 | 0.72 | PIN1 (0.49) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL1125293 | 0.72 | RORC (0.51) | MMP8PIN1ALDH1A1RECQLLMNA | |
| SCHEMBL9086579 | 0.71 | LMNA (0.51) | MMP8PIN1ALDH1A1RECQLCES2 | |
| SCHEMBL14826292 | 0.71 | KCNN4 (0.50) | ALDH1A1CYP1A2CYP2D6CYP3A4MAPT | |
| SCHEMBL8431510 | 0.71 | CYP4F2 (0.43) | MMP8PIN1ALDH1A1RECQLCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554624-A | CONGESTIVE HEART FAILURE; HYPOTENSIVE AGENTS | J. URIACH & CIA. (ES) | 1996-09-10 | — | — | US | disclosed |
| EP-0669333-A1 | New imidazopyridine derivatives as angiotensin II antagonists | J. URIACH & CIA. S.A. (ES) | 1995-08-30 | — | — | EP | disclosed |