Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.48 |
| ▸ | CES2 | O00748 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125975 | 0.97 | CES1 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL8788839 | 0.84 | SMN1; SMN2 (0.59) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9126860 | 0.79 | CES2 (0.37) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL543877 | 0.76 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL4269458 | 0.75 | ALDH1A1 (0.56) | CES1CES2ALDH1A1TDP1MAPT | |
| SCHEMBL611693 | 0.74 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL10443502 | 0.74 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL1165410 | 0.74 | CES1 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL8995168 | 0.73 | CES2 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL3035866 | 0.73 | CES2 (0.50) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469331-B1 | Process for preparing organic esters and amides and catalyst system therefor | MONTELL NORTH AMERICA INC (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5136082-A | PROCESS FOR PREPARING ORGANIC ESTERS AND AMIDES AND CATALYST SYSTEM THEREFOR | HIMONT INCORPORATED (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0469331-A1 | Process for preparing organic esters and amides and catalyst system therefor | MONTELL NORTH AMERICA INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-4659863-A | REACTING METHYL ACRYLATE AND HINDERED PHENOL IN PRESENCE OF ALKALI METAL ALKALINE CATALYST | ETHYL CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| US-4085132-A | Process for the production of hydroxyalkylphenyl derivatives | CIBA-GEIGY CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |