Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309076 | 0.74 | CA12 (0.43) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL8550054 | 0.73 | SLC22A12 (0.44) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL12013388 | 0.70 | HTT (0.47) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL679245 | 0.70 | ALDH1A1 (0.46) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL4437800 | 0.69 | ALDH1A1 (0.52) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL5964314 | 0.69 | HTT (0.46) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL8551230 | 0.67 | ALDH1A1 (0.44) | LMNAHTTSLC22A12MAPTSMN1; SMN2 | |
| SCHEMBL16540771 | 0.66 | MAPT (0.52) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18012132 | 0.65 | KDM4E (0.47) | MAPTSMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL16540660 | 0.65 | KDM4E (0.47) | MAPTSMN1; SMN2NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |