Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20070416 | 0.78 | KDM4E (0.36) | KDM4EFGF23MMP2TSHRCHRM1 | |
| SCHEMBL9000312 | 0.76 | NFE2L2 (0.49) | KDM4ENPC1MAPTRAB9AMAPK1 | |
| SCHEMBL9000369 | 0.76 | FGF23 (0.41) | KDM4EFGF23MMP2TSHRNPC1 | |
| SCHEMBL9000547 | 0.75 | MMP2 (0.47) | KDM4EFGF23MMP2TSHRCHRM1 | |
| SCHEMBL9000718 | 0.74 | KDM4E (0.50) | KDM4EMMP2TSHRCHRM1COMT | |
| SCHEMBL9000723 | 0.74 | KDM4E (0.50) | KDM4EMMP2TSHRCHRM1COMT | |
| SCHEMBL9000474 | 0.74 | KDM4E (0.50) | KDM4ETSHRNPC1MAPTRAB9A | |
| SCHEMBL3439424 | 0.72 | — | — | |
| SCHEMBL7216828 | 0.72 | — | — | |
| SCHEMBL5809339 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516409-B1 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5416213-A | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0516409-A2 | Tetravinylpyrazine compound, method for preparing same and electroluminescent element and non-linear optical material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-02 | — | — | EP | disclosed |