Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000423 | 0.92 | EPHX1 (0.44) | EPHX1MAPTSMN1; SMN2LMNAMMP13 | |
| SCHEMBL9000768 | 0.91 | EPHX1 (0.41) | EPHX1MAPTSMN1; SMN2LMNAMMP13 | |
| SCHEMBL9000729 | 0.91 | EPHX1 (0.41) | EPHX1MAPTSMN1; SMN2LMNAMMP13 | |
| SCHEMBL9000671 | 0.90 | EPHX1 (0.34) | EPHX1MAPTLMNAHTTPTGES | |
| SCHEMBL9000839 | 0.90 | SOAT1 (0.38) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9000878 | 0.88 | EPHX1 (0.41) | EPHX1MAPTSMN1; SMN2LMNAMMP13 | |
| SCHEMBL9000458 | 0.88 | EPHX1 (0.41) | EPHX1MAPTSMN1; SMN2LMNAMMP13 | |
| SCHEMBL9000398 | 0.88 | EPHX1 (0.47) | EPHX1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9000898 | 0.86 | EPHX1 (0.46) | EPHX1MAPTL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL9000777 | 0.85 | KMT2A (0.37) | LMNAMEN1KMT2ACYP1A2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |