Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000423 | 0.95 | EPHX1 (0.44) | EPHX1L3MBTL1MAPTSOAT1KDM4E | |
| SCHEMBL9000898 | 0.95 | EPHX1 (0.46) | EPHX1L3MBTL1MAPTSOAT1KDM4E | |
| SCHEMBL9000588 | 0.93 | EPHX1 (0.38) | EPHX1L3MBTL1SOAT1LMNA | |
| SCHEMBL9000651 | 0.92 | SOAT1 (0.41) | EPHX1SOAT1SMN1; SMN2 | |
| SCHEMBL9000878 | 0.91 | EPHX1 (0.41) | EPHX1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL9000458 | 0.91 | EPHX1 (0.41) | EPHX1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL9000768 | 0.91 | EPHX1 (0.41) | EPHX1L3MBTL1MAPTCNR2LMNA | |
| SCHEMBL9000506 | 0.90 | SOAT1 (0.39) | L3MBTL1SOAT1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9000575 | 0.90 | SOAT1 (0.39) | MAPTSOAT1KDM4EMEN1PKM | |
| SCHEMBL9000714 | 0.90 | GPR88 (0.39) | EPHX1L3MBTL1MAPTSOAT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583147-A | INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL O-TRANSFERASE; ANTIHYPERCHOLESTEROLEMIC AND/OR ANTIATHEROSCLEROTIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-10 | — | — | US | disclosed |