Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001214 | 0.80 | HTR2C (0.46) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL9001370 | 0.79 | ALDH1A1 (0.46) | HTR1AHTR1DHTR2BMEN1KMT2A | |
| SCHEMBL9001256 | 0.79 | HTR1A (0.68) | HTR1AHTR1DHTR2BMEN1KMT2A | |
| SCHEMBL7937294 | 0.74 | HTR1A (0.52) | HTR1AHTR1DHTR2BMEN1KMT2A | |
| SCHEMBL16167669 | 0.72 | HTR2C (0.46) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL11919645 | 0.71 | HTR2C (0.54) | HTR1AHTR2BMEN1KMT2AHTR2C | |
| Hydrochloric Acid SCHEMBL1661078 | 0.71 | HTR2C (0.47) | MEN1KMT2AALDH1A1LMNAHTR2C | |
| SCHEMBL28800047 | 0.67 | HTR2C (0.51) | HTR1AHTR2BMEN1KMT2AHTR2C | |
| SCHEMBL6546383 | 0.67 | HTR1A (1.00) | HTR1AHTR1DHTR2BALDH1A1LMNA | |
| SCHEMBL10401478 | 0.67 | PROKR1 (0.52) | MEN1KMT2AALDH1A1PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5585374-A | Amide derivatives | JOHN WYETH BROTHER, LIMITED (GB) | 1996-12-17 | — | — | US | claimed |