Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879474 | 0.90 | KDM4E (0.57) | SMN1; SMN2L3MBTL1HTTTRPV1KDM4E | |
| SCHEMBL9002596 | 0.84 | RORB (0.56) | SMN1; SMN2L3MBTL1KDM4ENPC1RAB9A | |
| SCHEMBL10726628 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1HTTTRPV1KDM4E | |
| SCHEMBL10094462 | 0.79 | TRPV1 (0.52) | SMN1; SMN2L3MBTL1HTTTRPV1KDM4E | |
| SCHEMBL9002488 | 0.79 | RORB (0.48) | TRPV1KDM4EGAAALDH1A1HPGD | |
| SCHEMBL9002411 | 0.79 | TRPV1 (0.51) | SMN1; SMN2TRPV1KDM4EGAANPC1 | |
| SCHEMBL9002089 | 0.78 | NR2E1 (0.46) | TRPV1ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL10969548 | 0.77 | RORB (0.60) | SMN1; SMN2L3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL8884154 | 0.76 | KDM4E (0.50) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11350077 | 0.76 | TRPV1 (0.49) | SMN1; SMN2L3MBTL1TRPV1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482948-A | Pyridyl derivatives and pharmaceutical compositions comprising these compounds | DR. KARL THOMAE GMBH (DE) | 1996-01-09 | — | — | US | disclosed |
| US-5286736-A | Thromboxane antagonists and thromboxane synthetase inhibitors | DR. KARL THOMAE GMBH (DE) | 1994-02-15 | — | — | US | disclosed |