Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 6/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002596 | 0.80 | RORB (0.56) | RXFP1ALDH1A1CYP1A2NFKB1RORB | |
| SCHEMBL9002107 | 0.78 | SMN1; SMN2 (0.53) | TRPV1POLBRXFP1MEN1ALDH1A1 | |
| SCHEMBL9002267 | 0.77 | RORB (0.56) | TRPV1LMNAPOLBMEN1GMNN | |
| SCHEMBL6224945 | 0.76 | TRPV1 (0.48) | KDREGFRFGFR1TUBB4ATUBB | |
| SCHEMBL9002406 | 0.75 | TRPV1 (0.44) | TRPV1LMNAMEN1ALDH1A1PKM | |
| SCHEMBL31729816 | 0.74 | PSEN1 (0.68) | NR2E1KDREGFRFGFR1 | |
| SCHEMBL5773763 | 0.72 | MAPT (0.67) | NR2E1LMNAALDH1A1GPR35P2RX1 | |
| SCHEMBL9002488 | 0.70 | RORB (0.48) | FGFR1TRPV1LMNAMEN1ALDH1A1 | |
| SCHEMBL9002078 | 0.70 | TRPA1 (0.57) | KDREGFRFGFR1RXFP1MEN1 | |
| SCHEMBL14861239 | 0.69 | TRPV1 (0.46) | FGFR1TRPV1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482948-A | Pyridyl derivatives and pharmaceutical compositions comprising these compounds | DR. KARL THOMAE GMBH (DE) | 1996-01-09 | — | — | US | disclosed |