Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002188 | 0.89 | ALDH1A1 (0.50) | KMT2AMEN1CTRB1ALDH1A1LMNA | |
| SCHEMBL9002042 | 0.88 | KMT2A (0.46) | KMT2AMEN1CTRB1ALDH1A1LMNA | |
| SCHEMBL9001915 | 0.83 | SMN1; SMN2 (0.46) | KMT2AMEN1CTRB1ALDH1A1LMNA | |
| SCHEMBL9810151 | 0.77 | SYK (0.60) | KMT2AMEN1CTRB1ALDH1A1LMNA | |
| SCHEMBL9001816 | 0.77 | CTRB1 (0.50) | KMT2AMEN1CTRB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10332296 | 0.73 | SYK (0.61) | KMT2AMEN1CTRB1ALDH1A1LMNA | |
| SCHEMBL8612085 | 0.71 | CTRB1 (0.60) | CTRB1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL8612079 | 0.71 | CTRB1 (0.60) | CTRB1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL17275393 | 0.71 | CTSS (0.55) | CTRB1ALDH1A1CTSLCTSBCTSS | |
| SCHEMBL14595243 | 0.71 | CTRB1 (0.74) | CTRB1ALDH1A1SYKCYP3A4CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731784-A1 | ARYL HALIDE SUBSTITUTED METALLIC COMPLEXES, PHARMACEUTICALS CONTAINING THESE COMPLEXES, THEIR USE FOR DIAGNOSTIC PURPOSES, AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015306-A1 | ARYL HALIDE SUBSTITUTED METALLIC COMPLEXES, PHARMACEUTICALS CONTAINING THESE COMPLEXES, THEIR USE FOR DIAGNOSTIC PURPOSES, AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |