SCHEMBL900267

SCHEMBL900267

[CH2]Cc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 7/20 0.41
CYP3A4 P08684 6/20 0.41
HSD17B10 Q99714 5/20 0.41
RECQL P46063 3/20 0.41
AHR P35869 4/20 0.36
HPGD P15428 3/20 0.36
TP53 P04637 3/20 0.35
MAPK1 P28482 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
ALOX15 P16050 2/20 0.32
ALOX12 P18054 2/20 0.32
CASP1 P29466 2/20 0.32
CASP7 P55210 2/20 0.32
KMT2A Q03164 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
IDO1 P14902 1/20 0.32
SLC22A2 O15244 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14992502 0.83 ALDH1A1 (0.36) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL6130333 0.78 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL29074259 0.75 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL6130331 0.74 ALDH1A1 (0.40) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL1589735 0.73 ALDH1A1 (0.47) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL9852668 0.72 PDE2A (0.36) ALDH1A1TSHRCYP3A4HPGDKDM4E
SCHEMBL10899786 0.72 ALDH1A1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL147261 0.72 TSHR (0.35) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL6650824 0.71 ALDH1A1 (0.37) ALDH1A1TSHRCYP3A4HSD17B10RECQL
SCHEMBL1044618 0.71 ALDH1A1 (0.45) ALDH1A1TSHRCYP3A4HSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-22 US disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2016-11-24 US disclosed
EP-2621922-A1 A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS BASF SE (DE) 2013-08-07 EP disclosed
WO-2012041858-A1 A PROCESS FOR THE SYNTHESIS OF THIO-TRIAZOLO-GROUP CONTAINING COMPOUNDS BASF SE (DE) 2012-04-05 WO disclosed
EP-2311816-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2311817-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2308858-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-13 EP disclosed
US-20100234220-A1 Oxooxetanes as Fungicidal Agents BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-4275148-A THIO SUBSTITUTED PYRAZOLINES AS MAGENTA COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-06-23 US disclosed
US-4264722-A A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4254212-A ALKOXY SUBSTITUTED SULFONYL FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
EP-0024033-A1 Photographic colour couplers and light-sensitive material containing them FUJI PHOTO FILM CO., LTD. (JP) 1981-02-18 EP disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4217410-A CYAN DYE COUPLER, PHOSPHATE SOLVENTS FUJI PHOTO FILM CO., LTD. (JP) 1980-08-12 US disclosed
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US disclosed
US-4072525-A COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1978-02-07 US disclosed
US-4032345-A SILVER HALIDE MATERIALS CONTAINING PHOTOGRAPHIC COLOR COUPLERS WITH ISOTHIOCYANATO GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed
US-3971825-A (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS SANKYO COMPANY LIMITED (JA) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL CYP4X1, PRDX5, PRDX1 ALDH1A1 1299/4885TSHR 2681/4885CYP3A4 95/4885
US-10451967-B2 Acid- and radical-generating agent and method for generating acid and radical CBR1, HAO2, CBR3 ALDH1A1 151/4885TSHR 648/4885CYP3A4 1029/4885
US-20160342084-A1 ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL CBR1, HAO2, CBR3 ALDH1A1 151/4885TSHR 648/4885CYP3A4 1029/4885
US-20100234220-A1 Oxooxetanes as Fungicidal Agents CYP51A1, PNPO, AOX1 ALDH1A1 950/4885TSHR 3912/4885CYP3A4 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.