Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.56 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003166 | 0.98 | HRH1 (0.57) | FDPSHRH1HRH3LMNACYP1A2 | |
| SCHEMBL8752552 | 0.95 | FDPS (0.57) | FDPSHRH1HRH3LMNACYP1A2 | |
| SCHEMBL932969 | 0.87 | FDPS (0.61) | FDPSHRH1HRH3LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5827595 | 0.83 | HRH1 (0.73) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| SCHEMBL726512 | 0.81 | HRH1 (0.76) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| SCHEMBL4418086 | 0.79 | HRH1 (0.80) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| SCHEMBL31040594 | 0.79 | HRH1 (0.80) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| SCHEMBL659243 | 0.79 | HRH1 (0.80) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| SCHEMBL2843489 | 0.79 | HRH1 (0.80) | HRH1HRH3LMNACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL841530 | 0.79 | HRH1 (0.67) | HRH1HRH3LMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353969-B1 | Catalytic amidation process | DU PONT (US) | 1994-06-08 | — | — | EP | claimed |
| US-4912175-A | Heating | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-27 | — | — | US | claimed |
| WO-1990001513-A1 | CATALYTIC AMIDATION PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-22 | — | — | WO | claimed |
| EP-0560933-B1 | PROCESS FOR INCREASING THE RELATIVE VISCOSITY OF POLYAMIDES | DU PONT (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0353969-B1 | Catalytic amidation process | DU PONT (US) | 1994-06-08 | — | — | EP | disclosed |
| EP-0560933-A1 | PROCESS FOR INCREASING THE RELATIVE VISCOSITY OF POLYAMIDES. | DU PONT (US) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992010526-A1 | PROCESS FOR INCREASING THE RELATIVE VISCOSITY OF POLYAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5116919-A | Heating in presence of base and phosphonate catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| US-4912175-A | Heating | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-27 | — | — | US | disclosed |
| WO-1990001513-A1 | CATALYTIC AMIDATION PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-02-22 | — | — | WO | disclosed |