Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139001 | 0.89 | CES1 (0.38) | NPC1RAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL8757349 | 0.88 | NPC1 (0.45) | NPC1RAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL9003605 | 0.86 | L3MBTL1 (0.40) | NPC1RAB9AKMT2AMEN1HSD11B1 | |
| SCHEMBL9003818 | 0.86 | ALDH1A1 (0.38) | NPC1RAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL9003693 | 0.83 | GSK3B (0.38) | NPC1RAB9AKMT2AMEN1HSD11B1 | |
| SCHEMBL9003419 | 0.81 | ICMT (0.33) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL9003355 | 0.80 | MEN1 (0.46) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9003416 | 0.79 | CES2 (0.33) | KMT2AMEN1CES2CES1PTGS2 | |
| SCHEMBL8757375 | 0.78 | L3MBTL1 (0.38) | NPC1RAB9AKMT2AMEN1CYP3A4 | |
| SCHEMBL8757317 | 0.76 | CES1 (0.40) | NPC1RAB9AKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500453-A | INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |