Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970600 | 0.82 | MEN1 (0.61) | NAAAMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL5708374 | 0.79 | SLC6A4 (0.36) | MEN1KMT2AHSD17B10ALDH1A1USP2 | |
| Phosphoric Acid SCHEMBL339543 | 0.77 | MEN1 (0.54) | NAAAMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL16488593 | 0.75 | — | — | |
| SCHEMBL9633210 | 0.73 | FAAH (0.59) | NAAAMEN1KMT2AFAAHMAPK1 | |
| SCHEMBL29113513 | 0.71 | — | — | |
| SCHEMBL23376623 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AFAAHMAPK1HSD17B10 | |
| SCHEMBL15435835 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AFAAHMAPK1HSD17B10 | |
| SCHEMBL18674704 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AFAAHMAPK1HSD17B10 | |
| SCHEMBL7786760 | 0.69 | HSD17B10 (0.31) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733045-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015952-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1995-06-15 | — | — | WO | disclosed |