Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889322 | 0.80 | KMT2A (0.68) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL8269548 | 0.80 | HSD11B1 (0.64) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL1095578 | 0.79 | TDP1 (0.54) | PARP1CES2CES1NPC1RAB9A | |
| SCHEMBL11248287 | 0.77 | CES2 (0.69) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL30758862 | 0.77 | CES2 (0.69) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL29207027 | 0.77 | NPC1 (0.76) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL1515775 | 0.77 | MEN1 (0.61) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL1421198 | 0.76 | CES2 (0.62) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL1305114 | 0.76 | CES2 (0.67) | HSD11B1PARP1CES2CES1NPC1 | |
| SCHEMBL733307 | 0.76 | CES2 (0.67) | HSD11B1PARP1CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500453-A | INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |