SCHEMBL9003442

SCHEMBL9003442

CCO[PH](=O)c1ccccc1C(C)Br

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777147 0.73 TSHR (0.35) TSHR
SCHEMBL779740 0.73 MAPT (0.39) TSHR
SCHEMBL13905535 0.72 ALDH1A1 (0.42) TSHR
SCHEMBL9003446 0.70 TDP1 (0.31)
SCHEMBL365389 0.69 RXRA (0.32)
SCHEMBL9559628 0.69 HPGD (0.41) ELANETSHR
SCHEMBL11505580 0.68 ALDH1A1 (0.34)
SCHEMBL27890273 0.67 ALDH1A1 (0.50)
SCHEMBL28269807 0.67 ALDH1A1 (0.41) ELANETSHR
Toluene SCHEMBL27878734 0.67 ALDH1A1 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733036-A1 ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS UNIVERSITY OF BRISTOL (GB) 1996-09-25 EP disclosed
WO-1995015940-A1 ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS UNIVERSITY OF BRISTOL (GB) 1995-06-15 WO disclosed