Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779740 | 0.84 | MAPT (0.39) | CYP4F2CYP4A11MAPTNPSR1L3MBTL1 | |
| SCHEMBL7916460 | 0.77 | HTR2A (0.41) | L3MBTL1 | |
| SCHEMBL11312254 | 0.77 | GABRA1 (0.36) | MAPTL3MBTL1GABRA1GABRB2 | |
| SCHEMBL777147 | 0.73 | TSHR (0.35) | TDP1MAPTL3MBTL1 | |
| SCHEMBL13905535 | 0.72 | ALDH1A1 (0.42) | TDP1L3MBTL1 | |
| SCHEMBL28541537 | 0.71 | ALDH1A1 (0.36) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL18317180 | 0.71 | MAPT (0.30) | MAPTNPSR1L3MBTL1 | |
| SCHEMBL28552223 | 0.70 | L3MBTL1 (0.37) | TDP1MAPTNPSR1L3MBTL1GABRA1 | |
| SCHEMBL9003442 | 0.70 | ELANE (0.31) | — | |
| SCHEMBL10452384 | 0.70 | LIPG (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733036-A1 | ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015940-A1 | ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |