Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183945 | 0.71 | L3MBTL1 (0.38) | ALDH1A1MAPTSMN1; SMN2RAB9ATDP1 | |
| SCHEMBL6226972 | 0.71 | HDAC1 (0.44) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8233747 | 0.69 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CFTRTSHRKDM4E | |
| SCHEMBL942894 | 0.69 | KMT2A (0.53) | ALDH1A1HSD17B10TSHRKDM4EPOLB | |
| SCHEMBL27320474 | 0.67 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL28756705 | 0.67 | L3MBTL1 (0.47) | MAPTGAANPC1RAB9ATDP1 | |
| SCHEMBL14088039 | 0.67 | MAPT (0.47) | ALDH1A1HSD17B10CFTRTSHRKDM4E | |
| SCHEMBL13233269 | 0.66 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CFTRTSHRKDM4E | |
| SCHEMBL7763429 | 0.66 | MEN1 (0.41) | ALDH1A1TSHRNPC1RAB9AL3MBTL1 | |
| SCHEMBL29568750 | 0.66 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521175-A | CHOLECYSTOKININS AND GASTRIN ANTAGONIST FOR PHYSIOLOGICAL DISORDERS | MERCK SHARP & DOHME LTD. (GB) | 1996-05-28 | — | — | US | disclosed |
| EP-0652873-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003447-A1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |