Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855000 | 0.89 | MAPT (0.47) | NPC1HPGDRAB9AGSK3BHDAC3 | |
| SCHEMBL1095578 | 0.81 | TDP1 (0.54) | NPC1HPGDRAB9AGSK3BHDAC3 | |
| SCHEMBL9003388 | 0.81 | GSK3B (0.47) | NPC1RAB9AGSK3BHSD11B1MAPT | |
| SCHEMBL9003818 | 0.79 | ALDH1A1 (0.38) | NPC1HPGDRAB9AGSK3BHSD11B1 | |
| SCHEMBL9003649 | 0.77 | KMT2A (0.59) | NPC1RAB9AGSK3BHSD11B1AKR1C3 | |
| SCHEMBL2404286 | 0.77 | MAPT (0.56) | NPC1HPGDRAB9AGSK3BHSD11B1 | |
| Perchlorate SCHEMBL9003749 | 0.75 | HSD11B1 (0.45) | NPC1HPGDRAB9AHSD11B1PTPN1 | |
| Perchlorate SCHEMBL9003671 | 0.75 | TDP1 (0.47) | NPC1HPGDRAB9AGSK3BHDAC3 | |
| SCHEMBL9003314 | 0.75 | MAPT (0.44) | NPC1HPGDRAB9AGSK3BHSD11B1 | |
| SCHEMBL9003842 | 0.74 | HSP90AA1 (0.44) | NPC1RAB9AHDAC3HDAC1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500453-A | INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |