SCHEMBL9003649

SCHEMBL9003649

Cc1ccc(C(=O)C[S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.59
NPC1 O15118 3/20 0.59
RAB9A P51151 3/20 0.59
MEN1 O00255 3/20 0.59
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
HSD11B1 P28845 1/20 0.50
GSK3B P49841 1/20 0.48
RECQL P46063 1/20 0.46
LMNA P02545 4/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 3/20 0.46
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSP90AA1 P07900 1/20 0.45
VCP P55072 1/20 0.45
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL8752338 0.94 KMT2A (0.53) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL8074580 0.89 RECQL (0.52) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL1095578 0.87 TDP1 (0.54) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL9003684 0.85 KMT2A (0.44) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL2404286 0.82 MAPT (0.56) KMT2ANPC1RAB9AMEN1CES2
Perchlorate SCHEMBL9003671 0.80 TDP1 (0.47) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL8855000 0.80 MAPT (0.47) KMT2ANPC1RAB9AMEN1CES1
SCHEMBL1127785 0.78 HSD11B1 (0.39) KMT2ANPC1RAB9AMEN1CES2
SCHEMBL2330045 0.78 GSK3B (0.53) KMT2ANPC1RAB9AMEN1HSD11B1
SCHEMBL30392819 0.77 KMT2A (0.58) KMT2ANPC1RAB9AMEN1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9058935-B2 Compounds containing alkyl-cyano-borate or alkyl-cyano-fluoroborate anions MERC PATENT GMBH (DE) 2015-06-16 US claimed
EP-2731955-B1 COMPOUNDS CONTAINING ALKYL-CYANO-BORATE OR ALKYL-CYANO-FLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2017-01-11 EP disclosed
US-9518068-B2 Compounds containing hydrido-tricyano-borate anions MERCK PATENT GMBH (DE) 2016-12-13 US disclosed
EP-2714698-B1 COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS MERCK PATENT GMBH (DE) 2016-11-09 EP disclosed
US-9409925-B2 Compounds containing hydrido-tricyano-borate anions MERCK PATENT GMBH (DE) 2016-08-09 US disclosed
US-20160167972-A1 COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS MERCK PATENT GMBH (DE) 2016-06-16 US disclosed
US-20150291515-A1 SALTS CONTAINING TRIHYDROPERFLUOROALKOXYBUTANESULFONATE OR TRIHYDROPERFLUOROALKOXYPROPANESULFONATE ANION MERCK PATENT GMBH (DE) 2015-10-15 US disclosed
US-9058935-B2 Compounds containing alkyl-cyano-borate or alkyl-cyano-fluoroborate anions MERC PATENT GMBH (DE) 2015-06-16 US disclosed
US-20140155566-A1 COMPOUNDS CONTAINING ALKYL-CYANO-BORATE OR ALKYL-CYANO-FLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2014-06-05 US disclosed
EP-2731955-A1 COMPOUNDS CONTAINING ALKYL-CYANO-BORATE OR ALKYL-CYANO-FLUOROBORATE ANIONS Merck Patent GmbH (DE) 2014-05-21 EP disclosed
US-20140107341-A1 COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS MERCK PATENT GMBH (DE) 2014-04-17 US disclosed
WO-2013010641-A1 COMPOUNDS CONTAINING ALKYL-CYANO-BORATE OR ALKYL-CYANO-FLUOROBORATE ANIONS MERCK PATENT GMBH (DE) 2013-01-24 WO disclosed
WO-2012163489-A1 COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS MERCK PATENT GMBH (DE) 2012-12-06 WO disclosed
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291515-A1 SALTS CONTAINING TRIHYDROPERFLUOROALKOXYBUTANESULFONATE OR TRIHYDROPERFLUOROALKOXYPROPANESULFONATE ANION STS, ARSA, TST KMT2A 3866/4885NPC1 4046/4885RAB9A 2374/4885
US-20140107341-A1 COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS HCN4, SLC9A3, HCN3 KMT2A 2340/4885NPC1 1342/4885RAB9A 640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.