SCHEMBL9003797

SCHEMBL9003797

O=[N+](O)c1ccc(C[S+](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.34
PTPRF P10586 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CRHBP P24387 2/20 0.32
CRHR2 Q13324 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 2/20 0.31
CES1 P23141 2/20 0.31
PLA2G10 O15496 1/20 0.31
PLA2G2A P14555 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003794 0.82 CYP2C19 (0.53) CYP2C19CYP1A2PTPRFPTPN2PTPN1
SCHEMBL10681251 0.77 CYP2C19 (0.47) CYP2C19CYP1A2PTPRFPTPN2PTPN1
SCHEMBL1127586 0.76 TSHR (0.46) ALDH1A1CES2CES1TSHR
SCHEMBL1127785 0.75 HSD11B1 (0.39) PTPN1ALDH1A1CRHBPCRHR2MEN1
Hydrochloric Acid SCHEMBL1042662 0.74 TSHR (0.43) ALDH1A1TSHR
SCHEMBL2323147 0.71 SIGMAR1 (0.44) CYP1A2ALDH1A1MEN1KMT2ATSHR
SCHEMBL2325029 0.71 ALDH1A1 (0.42) ALDH1A1TSHR
SCHEMBL11481750 0.71
SCHEMBL13981949 0.70 CES2 (0.42) CYP2C19CYP1A2ALDH1A1CES2CES1
Perchlorate SCHEMBL9003254 0.70 MEN1 (0.43) CYP2C19CYP1A2PTPRFPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4783529-A Rapid synthesis of radiolabeled porphyrin complexes for medical application RESEARCH CORPORATION TECHNOLOGIES (US) 1988-11-08 US claimed
US-5500453-A INITIATOR FOR PHOTOSENSITIVE FREE RADICAL CURING/ POLYMERIZATION OF UNSATURATED COMPOUNDS TOYO INK MANUFACTURING CO., LTD. (JP) 1996-03-19 US disclosed