Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 4/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003846 | 1.00 | SLC15A1 (0.47) | SLC15A1ALDH1A1LAP3ANPEPIDO1 | |
| SCHEMBL6432522 | 0.80 | LAP3 (0.49) | ALDH1A1LAP3ANPEPIDO1TSHR | |
| SCHEMBL28796023 | 0.80 | LAP3 (0.49) | ALDH1A1LAP3ANPEPIDO1TSHR | |
| SCHEMBL15198796 | 0.78 | ALDH1A1 (0.58) | SLC15A1ALDH1A1LAP3IDO1ELANE | |
| SCHEMBL15886220 | 0.78 | ALDH1A1 (0.58) | SLC15A1ALDH1A1LAP3IDO1ELANE | |
| SCHEMBL18091192 | 0.78 | ALDH1A1 (0.58) | SLC15A1ALDH1A1LAP3IDO1ELANE | |
| SCHEMBL355730 | 0.78 | ALDH1A1 (0.53) | SLC15A1ALDH1A1ANPEPIDO1 | |
| SCHEMBL353695 | 0.78 | ALDH1A1 (0.53) | SLC15A1ALDH1A1ANPEPIDO1 | |
| SCHEMBL728728 | 0.78 | ALDH1A1 (0.53) | SLC15A1ALDH1A1ANPEPIDO1 | |
| Methyl Alcohol SCHEMBL28469240 | 0.78 | S1PR2 (0.48) | ALDH1A1LAP3ANPEPIDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538958-A | NMDA antagonists | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-23 | — | — | US | disclosed |
| US-5500419-A | NMDA antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-03-19 | — | — | US | disclosed |
| EP-0418863-B1 | NMDA antagonists | MERRELL DOW PHARMA (US) | 1995-01-04 | — | — | EP | disclosed |
| US-5326756-A | R-4-oxo-5 phosphononorvaline used as NMDA antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-07-05 | — | — | US | disclosed |
| US-5095009-A | NMDA antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0418863-A2 | NMDA antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-03-27 | — | — | EP | disclosed |